Telomeres length and telomerase activity are currently considered aging molecular stigmata. Water is a major requirement for our body and water should be alkaline. Recent reports have shown that aging is related to a reduced water intake. We wanted to investigate the effect of the daily intake of alkaline water on the molecular hallmark of aging and the anti-oxidant response. We watered a mouse model of aging with or without alkaline supplementation. We show here that watering by using alkaline water supplementation highly improves aging at the molecular level. A progressive and apparently unstoppable process of becoming older day-by-day, also called aging, is indeed a physiological process common to almost all living beings, but Prokaryotes, Protozoans and algae that are innately immortal 1, 2. Previous literature strongly supports a conceivable multifactorial pathogenesis of aging including pre-determined and damage-related factors 3. From a molecular point of view, the structures that are directly involved in the cellular aging are telomeres 9, Telomeres are regions of highly repeated DNA at each end of chromosomes, which protect these regions from recombination, degradation and inter-chromosomal fusion 5, 6,
Supplementary Data 5. Ovaries were isolated from the remaining reproductive system with a cutter and then disrupted with the blunt end of a 5-ml syringe plunger. There is no rule for setting the weights for different erosion severities. Interestingly, highly alkaliphilic bacteria, including some obligate alkaliphiles, have also been isolated from garden soils or other non-extremophilic settings. J Int Med Res. Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water. Protection of mammalian telomeres. Hydrogen concentration profiles at the oxic-anoxic interface: a microsensor study of the hindgut of the wood-feeding lower termite reticulitermes flavipes kollar Appl Environ Microbiol. Growth and bioenergetics of alkaliphilic Bacillus firmus OF4 in continuous-culture at high pH. Nonfermentative thermoalkaliphilic growth is restricted to alkaline environments. The other different finding in 8-OHdG test was that the group G had similar level with group F, which might indicate both groups had background level of 8-OHdG. The spring waters discharged from the sub-surface contain calcium as the result of serpentinization.
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