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Finding yourself confused by the seemingly endless promotion of weight-loss strategies and diet plans? In this series, we take a look at some popular diets—and review the research behind them. In the 19 th century, the ketogenic diet was commonly used to help control diabetes. In it was introduced as an effective treatment for epilepsy in children in whom medication was ineffective. However, this diet is gaining considerable attention as a potential weight-loss strategy due to the low-carb diet craze, which started in the s with the Atkins diet a very low-carbohydrate, high-protein diet, which was a commercial success and popularized low-carb diets to a new level. Today, other low-carb diets including the Paleo, South Beach, and Dukan diets are all high in protein but moderate in fat. The brain demands the most glucose in a steady supply, about grams daily, because it cannot store glucose. During fasting, or when very little carbohydrate is eaten, the body first pulls stored glucose from the liver and temporarily breaks down muscle to release glucose. If this continues for days and stored glucose is fully depleted, blood levels of a hormone called insulin decrease, and the body begins to use fat as its primary fuel.
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