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The human microbiome, or gut environment, is a community of different bacteria that has co-evolved with humans to be beneficial to both a person and the bacteria. What we eat, especially foods that contain chemical additives and ultra-processed foods, affects our gut environment and increases our risk of diseases. Ultra-processed foods contain substances extracted from food such as sugar and starch, added from food constituents hydrogenated fats, or made in a laboratory flavor enhancers, food colorings. These foods are very common in the typical Western diet. Some examples of processed foods are canned foods, sugar-coated dried fruits, and salted meat products. Some examples of ultra-processed foods are soda, sugary or savory packaged snack foods, packaged breads, buns and pastries, fish or chicken nuggets, and instant noodle soups. They suggest eating whole foods and avoiding processed and ultra-processed foods that we know cause inflammation and disease. In the relatively new field of nutritional psychiatry we help patients understand how gut health and diet can positively or negatively affect their mood. When someone is prescribed an antidepressant such as a selective serotonin reuptake inhibitor SSRI, the most common side effects are gut-related, and many people temporarily experience nausea, diarrhea, or gastrointestinal problems.