These supplements can be useful, but the effects are modest at best. The most common ones are Contrave, Phentermine, and Qsymia. They tend to work via one or more of these mechanisms: Reduce appetite, making you feel more full so that you eat fewer calories Reduce absorption of nutrients like fat, making you take in fewer calories Increase fat burning, making you burn more calories Here are the 12 most popular weight loss pills and supplements, reviewed by science. More research is needed. Similar item to consider. How are ratings calculated? There are a number of weight loss pills that have credible science behind. Alexa Actionable Analytics for the Web. So it is probably best to check and verify claims before purchasing the product. More From Discover. The Boiled Egg Diet is a popular fad diet that promises fast weight loss.
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We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. These are claimed to help you lose weight, or at least make it easier to lose weight combined with other methods. Garcinia cambogia became popular worldwide after being featured on the Dr. Oz show in The skin of the fruit contains hydroxycitric acid HCA. This is the active ingredient in garcinia cambogia extract, which is marketed as a diet pill. How it works: Animal studies show that it can inhibit a fat-producing enzyme in the body and increase levels of serotonin, potentially helping to reduce cravings 1, 2. Effectiveness: One study with people compared garcinia against a dummy pill. There was no difference in weight or body fat percentage between groups 3.